Ep 14. The Brain Eater

NOVA season 25 episode 14, titled "The Brain Eater," explores the mysterious disease known as Creutzfeldt-Jakob disease, or CJD. This neurodegenerative disorder is caused by a misfolded protein called a prion that invades and destroys the brain, leading to rapidly progressing dementia and eventual death.

The episode delves into the history of CJD, starting with the first known case in the early 20th century. Viewers learn about the pioneering work of German neurologist Alfons Maria Jakob, who made significant strides in understanding the disease and its pathology.

The episode also introduces several individuals who have been affected by CJD. Through their stories, viewers gain an understanding of just how devastating the disease can be. One woman lost several family members to CJD, including her mother, sister, and two brothers. She describes feeling helpless as she watched them deteriorate before her eyes, and shares her hopes that more research will be done to find a cure. Another individual affected by CJD is a former surgeon who was forced to retire early due to the disease. He discusses how difficult it was to come to terms with the fact that he would no longer be able to practice medicine, and his fears about what the future may hold for him.

Throughout the episode, viewers also learn about the science behind CJD. They explore the complexities of prions and the ways in which they can spread and replicate, both within the body and between individuals. They hear from scientists who are working tirelessly to understand the disease and find a cure, as well as from individuals who have taken it upon themselves to raise money and awareness for CJD research.

Overall, "The Brain Eater" offers a fascinating look not only at the science behind CJD, but also the impact it can have on individuals and families. It provides hope for a better future, one in which a cure for CJD may be found, but also highlights the urgent need for continued research and funding in the field.