Ep 5. Rare Anatomy: Bones

Imagine breaking a rib just by coughing or having an internal organ turning to bone. These are just two of the many life-threatening challenges faced by Jake Grys and Holly Pullano, two people with extraordinary genetic bone disorders. Jake is a spirited 9-year-old boy who has broken practically every bone in his body, and Holly is a 28-year-old whose muscles and tendons can turn to bone after the slightest impact. Using advanced animation, National Geographic travels inside Jake's diminutive frame to discover what make his bones so brittle and explores Holly's inner workings to find out how organs can turn into bone, progressively encasing her in a second skeleton.