Ep 1. My Leg Weighs 200 Pounds

In the season 3 premiere of Body Bizarre, we meet several individuals who are living with extraordinary medical conditions that are impacting their everyday lives. The episode is entitled "My Leg Weighs 200 Pounds" and focuses on the story of Mandy Sellars, a woman from the United Kingdom who was born with a rare genetic disorder that causes her legs to grow out of proportion with the rest of her body.

Mandy was initially diagnosed with Proteus Syndrome, a condition that causes abnormal growth of bones and skin, but doctors later determined that she actually has a different disorder called PIK3CA-Related Overgrowth Spectrum (PROS). This condition causes her leg to continue growing, even though the rest of her body stopped years ago. Mandy's leg currently weighs over 200 pounds, making it extremely difficult for her to move around and live a normal life.

The episode follows Mandy as she travels to the United States to meet with a team of doctors who specialize in treating PROS. She hopes that they will be able to provide her with some relief from the constant pain and discomfort that she experiences due to her condition.

In addition to Mandy's story, the episode also features several other individuals who are living with unique medical conditions. We meet a man with a rare disorder that causes his skin to become pigmented in a specific pattern, resembling a map. We also meet a woman who was born without arms and legs, but has learned to use her mouth to do everyday tasks like brushing her teeth and applying makeup.

Throughout the episode, we see the challenges that each of these individuals faces on a daily basis. From struggling to find clothes that fit to dealing with constant stares and questions from strangers, their lives are far from easy. However, they all remain determined to live as normal a life as possible, despite their conditions.

Overall, "My Leg Weighs 200 Pounds" is a touching and inspiring episode that highlights the strength and resilience of the human spirit. It is a testament to the fact that, no matter what challenges we face in life, we have the ability to overcome them with grace and determination.